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ENZYMAX REFLUX

Natural Solution for GERD Management

The combination of Opuntia ficus indica, Olea europaea, sodium alginate, bicarbonate, calcium carbonate, and microbial enzymes provides a comprehensive solution for managing GERD and improving gastrointestinal well-being.

Challenges and Alternatives in Managing Gastroesophageal Reflux (GER)

Gastroesophageal reflux (GER) is a chronic condition caused by the involuntary passage of gastric content into the esophagus, affecting up to 30% of the population.

Its typical symptoms, including heartburn and regurgitation, can disrupt daily activities and sleep, sometimes leading to complications like esophageal strictures and dysphagia.

GER often overlaps with dyspepsia, a condition marked by upper gastrointestinal symptoms such as abdominal pain, nausea, and early satiety, complicating diagnosis and treatment. The use of NSAIDs exacerbates this overlap, making natural treatment solutions appealing for affected individuals.

Management of GER primarily focuses on reducing esophageal acid exposure via proton pump inhibitors (PPIs) or acid neutralizers. The problem is that PPIs are not effective for most of patients, that experience breakthrough symptoms. It’s prolonged use carries risks, including vitamin B12 deficiency, infections, fractures, and adverse cardiac effects.

This highlights the need for alternative and sustainable therapeutic strategies.

Understanding Gastrointestinal Disorders: Key Terms and Conditions

Conditions like GERD and its non-erosive subtype NERD involve acid reflux causing discomfort, while dyspepsia refers to upper abdominal pain or indigestion. Persistent symptoms despite treatment (refractory antacid therapy) or nighttime acid production (nocturnal acid breakthrough) can complicate management.

  • Gastroesophageal reflux (GERD)
  • Non-erosive reflux disease (NERD)
  • Dyspepsia
  • Refractory antacid therapy
  • Nocturnal acid breakthrough

Key Ingredients for Gastric Protection

The combination of natural extracts like Opuntia ficus indica and Olea europaea, along with sodium alginate, digestive enzymes, and glycine, provides effective gastric support by reducing acid reflux, improving digestion, and protecting the esophagus.
  • The blend of Opuntia ficus indica and Olea europaea is formulated to protect the gastric mucosa. Opuntia ficus indica, helps to enhance gastric mucus production and exhibits anti-inflammatory and cytoprotective effects. Olea europaea leaf extract, rich in bioavailable polyphenols like oleuropein and flavonoids, has strong antioxidant properties and contributes to gastroprotection by reducing oxidative stress and inflammation.
  • Sodium alginate, combined with bicarbonate and calcium carbonate, forms a floating gel that acts as a physical barrier, preventing acid reflux and providing prolonged symptom relief by neutralizing stomach acidity.
  • Digestive enzymes such as fungal-derived lipases, proteases, amylases, and glucoamylases improve digestion under acidic conditions. These enzymes ensure efficient breakdown of fats, proteins, and carbohydrates, reducing symptoms like flatulence, bloating, and abdominal discomfort related with dyspepsia.

Clinical Studies

Opuntia ficus indica (O. ficus indica):

– Investigate the anti-ulcer and anti-inflammatory properties of mucilage derived from O. ficus indica, particularly its role in protecting gastric mucosa.

– Assess mechanisms such as restoration of membrane enzymes, lipid composition, and histological healing in ethanol-induced gastric damage.

 Conclusions:

   – O. ficus indica mucilage enhances gastric mucus production, forming a viscous protective layer against harmful agents (e.g., ethanol).

   – Promotes healing by stabilizing gastric epithelial surfaces, restoring membrane enzymes, and maintaining membrane fluidity.

   – Demonstrated anti-inflammatory effects that support recovery from gastritis.

Olea europaea (Olive Leaf Extract):

  – Study the gastroprotective effects of olive leaf extract on cold restraint stress (CRS)-induced gastric lesions in animal models.

  – Explore its antioxidant properties (e.g., oleuropein and flavonoids) and their potential to prevent oxidative damage.

 Conclusions:

 – Olive leaf extract reduced gastric lesions, prevented lipid peroxidation (measured by malondialdehyde levels), and maintained antioxidant enzyme activities   (catalase, superoxide dismutase).

 – Its protective effects are attributed to its potent antioxidant and anti-inflammatory components, which perform synergistically.

Clinical Studies with the Combined Extract

 – Evaluate the efficacy of a standardized blend of O. ficus indica and O. europaea in improving symptoms of gastrointestinal discomfort and GERD.

 Conclusions:

   – In a study with 100 participants, those receiving the extract showed significant improvements in GERD symptoms (heartburn, reflux, bloating) as measured by GSAS and GIQLI scores compared to placebo. Symptom relief was observed as early as 4 weeks, with further improvements at 8 weeks.

   – Short-Term Study: After two weeks of supplementation, subjects reported improvements in overall well-being and specific GERD symptoms (e.g., reduced heartburn and swelling) within days.

   – Combination Study with Sodium Alginate/Bicarbonate:A two-month randomized trial showed significant reductions in GERD symptoms, with a 70% reduction in heartburn and acid regurgitation episodes. The combination therapy was well-tolerated with no adverse effects.

How Does ENZYMAX REFLUX Works?​​

ENZYMAX REFLUX supports digestive health and provides relief for GERD, NERD, and related conditions. Follow the recommended dosage and consult a doctor if needed.

Enzymax reflux provides a comprehensive solution for managing GERD and improving gastrointestinal well-being.
The combination of Opuntia ficus indica, Olea europaea, sodium alginate, bicarbonate, calcium carbonate, and microbial enzymes provides a comprehensive solution for managing GERD and improving gastrointestinal well-being.
It is aimed at people with: Gastroesophageal reflux (GERD), non-erosive reflux disease (NERD), dyspepsia, refractory antacid therapy and nocturnal acid breakthrough
Take one or two tablets per meal, of Enzymax Reflux one hour after your meal.
It is recommended not to exceed the stated recommended daily dose. Food supplements should not replace a varied and balanced diet and a mode healthy life. Keep in a cool and dry place, below 25ºC and protect from sunlight and direct heat. Keep out of reach of children. Consult your doctor if you are on medication, pregnant, breastfeeding or suffer from food allergies. Do not use if you are allergic to any of the ingredients. According to the technical information available, these are well-tolerated ingredients with no side effects at the indicated doses. There are no known interactions of this product with other medicines or substances.

About Aora Aora Health

Nutraceutical Research and Development Company

We create innovative, scientifically proven solutions with specific benefits designed to complement or replace pharmaceuticals.

Our mission is to improve people’s well-being through nutraceutical products with proven benefits and backed by science.